Guna-Collagen (10pcs.*2ml.)

1. Indications and Usage for Guna Collagen

1.1. Skin tone improvement

1.2. Treatment of face and neck wrinkles

1.3. Stimulation of connective tissue metabolism.

2. Guna Collagen Dosage and Administration

2.1. Skin tone improvement for IM administration: 1 vial 1-3 times a week according to severity and clinical progress.

2.2. Treatment of face and neck wrinkles using mesotherapy technique: 1 vial. Using a 4 mm, 30G needle, make the classic intradermal injections utilizing mesotherapy technique.

2.3. Treatment of neck wrinkles using mesotherapy technique: 0.3 ml per wrinkle/cannulation. Using a 13 mm, 30G needle, insert the needle beneath the skin the full length of the needle, cannulate the wrinkle by moving the needle gently to left and right, while injecting the content of the syringe (tunnelling technique) as the needle is withdrawn.

2.4. Standard protocol according to mesotherapy technique consists of one session a week for 5-7 weeks. For prolonged treatments, 2 sessions for the first week, 1 session a week for 1 month and then 1 session a month are recommended.

Discard unused solution.

2.5. Opening of Vials: Use sterile needles and sterile syringe. Do not reuse. Do not use if foreign particles are present. Draw 1 cc of air into syringe, insert needle into vial inject air and withdraw the solution into the syringe.

Active ingredient: Collagen 6X.

Inactive ingredient: Sterile isotonic sodium chloride solution.

3. Contraindications

3.1. There is no history of hypersensitivity to GUNA®-COLLAGEN. However patients with a known hypersensitivity to any ingredient should be tested before use. Make a spot injection (0.1ml) into the forearm and observe for any reactions for 1 hour.

4. Warnings and Precautions

4.1. Be sure to disinfect the area before application. After treatment, avoid alcohol containing disinfectants as they produce local irritation that appears unpleasant on face. In most cases, the slight irritation disappears within 2 hours.

4.2. Skin disinfection is required before application. Saprophytic bacteria may produce injection site abscesses with improper skin preparation.

5. Adverse Reactions/Side Effects

5.1. The most common mild adverse reaction is slight reddening at the injection site due to the mechanical effect of the needle or a superficial skin reaction of mild erythema.

Collagen as an injectable application is widely used for treatment of wrinkles. The use of the homeopathic attenuation is an extension of the traditional application, where the effect on wrinkles is due to improvement of the metabolism of the area of application not to a filling activity. The skin gets a shining and vitalizing aspect that lasts from 3 to 6 months after the end of the protocol, depending on the patient’s habits and skin situation before treatment.

Store at room temperature, 20-25°C (68-77° F). Avoid freezing and excessive heat.